Set your oven to 425°F and let it warm up.
Spread the melted butter evenly in a deep 9x13 inch baking dish and add the cubed chicken. Season the chicken with 1 tablespoon Italian seasoning, 1 tablespoon garlic powder, onion powder, salt, black pepper, and chili flakes to taste.
Layer the dry noodles and broccoli florets over the seasoned chicken. Pour 1 1/2 cups of water on top to help cook the pasta.
In a separate bowl, whisk together the melted cream cheese, heavy cream, whole milk, and grated Parmesan cheese. Stir in extra Italian seasoning if you'd like. Pour this creamy mixture over the noodles and broccoli, then sprinkle the shredded mozzarella or provolone evenly on top. Dust with additional garlic powder.
Cover the dish with a lid or foil and bake for 30 minutes. Then uncover and continue baking for another 15 to 20 minutes until the cheese on top is nicely browned and the noodles begin to crisp.
Garnish the casserole with chopped fresh parsley or basil before serving. Scoop out and enjoy your comforting meal!