Warm up your skillet over medium-high heat.
In a bowl, combine the ground beef with garlic powder, salt, and pepper; mix thoroughly.
Divide the seasoned meat into 8 equal portions.
Flatten one portion of meat onto the top side of a tortilla, covering it completely.
Do the same for the remaining meat and tortillas.
Place each tortilla with meat side down onto the hot skillet. Cook for about 3 to 4 minutes, pressing down with a spatula to smash the burger thin.
Flip each burger over, place a slice of American cheese on top, then cook for an additional 2 to 3 minutes until the tortilla is crispy and the cheese has melted.
Meanwhile, combine mayonnaise, finely chopped pickles, yellow mustard, sugar-free ketchup, vinegar, paprika, garlic powder, and onion powder in a bowl; mix well.
Spread the prepared keto Big Mac sauce evenly over each smash burger.
Top the burgers with shredded lettuce and add two dill pickle slices on each before serving.
